Novel method for non-invasive induction of a middle-ear biofilm in the rat.

In Vitro Streptococcus pneumoniae Biofilm Formation and In Vivo Middle Ear Mucosal Biofilm in a Rat Model of Acute Otitis Induced by S. pneumoniae

OBJECTIVES Streptococcus pneumoniae is one of the most common pathogens of otitis media (OM) that exists in biofilm, which enhances the resistance of bacteria against antibiotic killing and diagnosis, compared to the free-floating (planktonic) form. This study evaluated biofilm formation by S. pneumoniae on an abiotic surface and in the middle ear cavity in a rat model of OM. METHODS In vitro...

Non-invasive optical interferometry for the assessment of biofilm growth in the middle ear

Otitis media (OM) is the most common illness in children in the United States. Three-fourths of children under the age of three have OM at least once. Children with chronic OM, including OM with effusion and recurrent OM, will often have conductive hearing loss and communication difficulties, and need surgical treatment. Recent clinical studies provide evidence that almost all chronic OM cases ...

Stator Turn-to-Turn Fault Detection of Induction Motor by Non-Invasive Method Using Generalized Regression Neural Network

Condition monitoring and protection methods based on the analysis of the machine's current are widely used according to non-invasive characteristics of current transformers. It should be noted that, these sensors are installed by default in the machine control center. On the other hand, condition monitoring based on mathematical methods has been proposed in literature. However, they are model b...

Non-invasive Assessment of Bacterial Biofilm in the Middle Ear Using Low-coherence Interferometry/optical Coherence Tomography and Acoustic Measurements by Cac Thi Nguyen Dissertation

Investigation of bacterial biofilm in the human middle ear using optical coherence tomography and acoustic measurements.

Children with chronic otitis media (OM) often have conductive hearing loss which results in communication difficulties and requires surgical treatment. Recent studies have provided clinical evidence that there is a one-to-one correspondence between chronic OM and the presence of a bacterial biofilm behind the tympanic membrane (TM). Here we investigate the acoustic effects of bacterial biofilms...